Resolution: When Vijeo Designer Runtime Simulation cannot start, it is possible that a system file is missing. In one situation, the "ewfapi.dll" file can be missing. This can prevent the runtime simulation from starting. To resolve this, please copy the file "ewfapi.dll" from "C:\Program Files\Schneider Electric\Vijeo-Designer\Vijeo-Frame\" to "C:\Program Files\Schneider Electric\Vijeo-Designer\Vijeo-Runtime\public\bin"